View enhanced pdf access article on wiley online library html view download pdf for offline viewing. Effective pain management in haemophilia is essential to reduce the burden that pain imposes on patients. Hemophilia hemophilia a and b are genetic disorders of clotting factors viii and ix, respectively. Jul 21, 2016 joint pain is common in haemophilia and may be acute or chronic. However, the choice of appropriate painrelieving measures is challenging, as there is a complex interplay of factors affecting pain perception. Massimo morfini this study aimed to identify the characteristics of patients with hemophilia b eligible for onceweekly treatment with nonacog alfa. Derlon, and enza rossi provided their own patient information and participated in the discussion and to. Massimo morfini at associazione italiana centri emofilia. Safety of recombinant coagulation factors in treating hemophilia. Este trastorno no es curable, pero tampoco es fatal. Diagnosis and care of patients with mild haemophilia.
Carrier detection and prenatal diagnosis by dna analysis blood, vol 70, no 2 august. Cryoprecipitate and factor viii commercial concentrates. The incidence of hemophilia a and b is about 15000 males worldwide and affects individuals of all races. Pain and pain management in haemophilia pubmed central pmc. Na hemofilia a, ocorre deficiencia do fator viii fviii, e na hemofilia b, do fator ix fix. Pdf the italian aicegenetics hemophilia a database. Pdf background fusengo is a relatively new device consisting of a prefilled. A deficiencia do fator 8 e a causa da hemofilia do tipo a e a deficiencia do fator 9 esta relacionada com a hemofilia do tipo b. Disclosures of massimo morfini emofilia nel nuovo millennio 6767v070600060 reggio calabria, 12 ottobre 2016 ii congresso interregionale 1. Hemofilia by nidia carolina mendez quezada on prezi. According to the degree of fviii deficiency, mild, moderate or severe forms are. A hemofilia nao tem cura e a base do seu tratamento e a infusao do concentrado do fator deficiente. Annarita tagliaferri, ezio zanon 14 and massimo morfini 15.
A hemofilia b e uma doenca causada pela mutacao no gene do fator ix. Martorell, antonio scaraggi, carmen altisent, jan blatny, annie borel. Management of bleedings in patients with hemophilia in the emergency room. Joint pain is common in haemophilia and may be acute or chronic. Fviii and fix are either defective or made in insufficient amounts, resulting in impaired secondary hemostasis. Prophylactic treatment of haemophilia patients with inhibitors. Morfini massimo set up the questionnaires, coordinated the study group and wrote the paper. Identification of the profile of the patients with hemophilia b. European study on orthopaedic status of haemophilia. Prophylactic treatment of haemophilia patients with. Clinical use of factor viii and factor ix concentrates. European study on orthopedic status of hemophilia patients with inhibitors. Pharmacokineticbased prediction of reallife dosing of extended halflife clotting factor concentrates on hemophilia.
Safety and pharmacokinetics of a novel recombinant fusion protein. Morfini m 2016 a new era in the hemophilia treatment. Massimo morfini, agency for hemophilia and regional. Articular status of haemophilia patients with inhibitors. Dr massimo morfini, agenzia per lemofilia, azienda ospedaliero universitaria careggi, viale g. Massimo morfini, md, agency for haemophilia, azienda ospedaliera universitaria careggi, viale g. Centro emofilia, divisione di ematologia, ospedale di careggi, viale morgagni 85, 504, firenze, italia. Pdf patient satisfaction and acceptability of an ondemand and on. Hemophilia a is an xlinked hereditary bleeding disorder due to the deficiency of coagulation factor viii fviii. Pharmacokineticbased prediction of reallife dosing of. Hemophilia free download as powerpoint presentation. Massimo morfini, md, agency for hemophilia reference center for inherited bleeding disorders of tuscany, department of emergency and reception, azienda ospedaliero universitaria careggi, firenze, italy. Clinical use of factor viii and factor ix concentrates ncbi. Pdf the high mutational heterogeneity of hemophilia a is a challenge for the provision of genetic.